Special Report on the “The Asian Age”
Recently, the American Chemical Society's exclusive news weekly (ACS Weekly), the International Science Daily (Science Daily), the Asian Age (The Asian Age), the International Wisdom Oral (Tooth Wise) and other international media, have reported the latest development of our school's light teeth Non-destructive whitening technology. The technology was developed by the Biomaterials Laboratory of the Institute of Translational Medicine of Nanchang University (team leader: Professor Wang Xiaolei) and the affiliated dental hospital of Nanchang University (team leader: Professor Liao Wei) and other institutions. Nanchang University is the only research and development unit.
he core accomplisher of this technology
In recent years, more and more people choose to whiten their teeth because the color of their teeth is not ideal. Currently, more than 30% hydrogen peroxide and high intensity blue light are used in clinical tooth whitening. High concentration of hydrogen peroxide is highly corrosive and oxidative, although it can effectively whiten, but its action is too intense, which can easily induce a series of problems, such as enamel demineralization, tooth sensitivity, gingival stimulation, cytotoxicity, and acute pulpitis and other adverse reactions. Therefore, it is urgent to find a new type of biomedical material that can respond to visible light, but at the same time has low stimulation and low toxicity, so as to achieve non-destructive whitening of teeth in a real sense.
Schematic illustration of non-destructive whitening technique for light teeth
In response to this topic, Professor Wang Xiaolei and Professor Liao Wei of our school first proposed to use PDA to encapsulate and modify the surface of nano-TiO2 to excite electrons under visible light to produce active oxygen with strong oxidative properties, thereby efficiently decomposing pigments. The effect of tooth whitening, the pH of the material is alkaline, non-corrosive, almost no damage to the surface structure of the enamel, low cytotoxicity, and better safety than the hydrogen peroxide bleach commonly used in clinical practice.
Nano-TiO₂@PDA whitening effect sketch(On the left is the whitened teeth)
Immediately after the introduction of the technology, it attracted a lot of attention from many international media. The only official news media of the American Chemical Society, ACS Weekly wrote a special article on the topic of “a safe and effective method of whitening teeth” and pointed out: “ Nanchang University has developed a visible light-responsive photocatalytic material for tooth whiten, which subverts the traditional peroxide whitening, which is not only effective but also milder."
“Science Daily” also reported on the related content, pointing out that “The Nanchang University team has developed a new whitening material that is less harmful to teeth in response to the defects of existing oral whitening materials.”
"Tooth Wise", an internationally authoritative oral professional organization, also made a special report on related research, and once again stressed: "The existing tooth whitening materials have certain damage to the teeth, and the research from Nanchang University has effectively reduced. The risk of this injury.” Dr. Amin, the chief scientist of the British Innovative Dental Medical Co., wrote a letter to apply for a technology share, hoping to bring the technology to the UK as soon as possible.
The core highlight of this study: no significant damage to the enamel surface after whitening by Nano-TiO2@PDA.
Professor Liao Wei said that in future research, we will further optimize the way we use it and systematically evaluate the long-term biosafety and whitening effect of this material.
Glowing toothbrush samples developed by National LED Engineering Center of Nanchang University
Professor Wang Xiaolei said that this technology is another breakthrough in the field of light health materials technology. At present, the first round of financing has been opened in China. It is worth mentioning that in the National LED Engineering Center of Nanchang University (Mei Luyao), Qingzheng Company (Liu Yang), the research team of Dr. Yu Fen, Ye Fanglin and other related personnel, we have prepared a batch of built-in High-efficiency LED chip light-emitting toothbrush samples not only improve the technical threshold, but also facilitate the popularization of this technology, so that more people can have healthy and bright white teeth more conveniently.
"Finally, do a little spoiler," Professor Wang Xiaolei said with a laugh. "We have achieved some interesting experimental results in the light precise hair-generating technology (not necessarily hair, eyebrows and eyelashes can also be oh) of our special subject area. Please look forward to it."
Brief introduction of main project completors
Wang Xiao Lei
Professor Ganjiang, Nanchang University, Professor, Doctor, Member of the Youth Work Committee of the 93 Society, Millions of Talents, Young Jinggang Scholars, Outstanding Youth and Top Talents of the Province; In 2009, he graduated from Changchun Yinghua Institute of Chinese Academy of Sciences (academician Yang Xiurong), and is currently the assistant dean of the Institute of Translational Medicine of Nanchang University. He is also the director of the National Special Zone of Double-Top Disciplines of Light and Health New Materials Technology of Nanchang University. He is also an expert in the defense evaluation of the National Award Office and the defense evaluation of the Ministry of Science and Technology in the Experts, specialists of 3D printing Research Institute of Ministry of Industry and Information Technology, specialists of direction evaluation of biomaterials of State Fund Committee, etc.Long-term commitment to the application and transformation of nanomaterials combined with 3D printing technology in the field of biomedicine. Now published in Advanced Materials (IF=19.791), ACS Nano (IF=13.942), Advanced Functional Materials (IF=12.124) and other SCI international journals, 29 papers or communication author papers, with an average impact factor of 7.10, patent application 12 items.
Liao Lan
Professor, Chief Physician, Doctoral Tutor, Secretary of the Party Committee of Dental Hospital Affiliated to Nanchang University. In 1993, she graduated from the Department of Stomatology, Medical College of Nanchang University. In 2010, she graduated from the School of Material Science and Engineering, Nanchang University with a master's degree in Material Physics and Chemistry. In 2015, she graduated from the School of Material Science and Engineering, Nanchang University with a doctoral degree in Material Physics and Chemistry. She has been awarded the title of "one million talents of jiangxi province", the model of female achievement of jiangxi province, the backbone teacher of middle and young people in institutions of higher learning of jiangxi province, the training object of academic and technical leader of health system of jiangxi province, and the member of leading discipline of medicine of jiangxi province. She has visited the UK, Australia, South Korea, the United States and other countries for academic visits and exchanges. In 2015-2016, she was sent to the School of Dentistry of Temple University in the United States as a visiting scholar for a year by the “100-person Long-distance Engineering” talent project of Jiangxi Province. She has been engaged in the clinical treatment, teaching and research of oral diseases for a long time, and is good at diagnosis and treatment of various oral repair incurable diseases. In the early days, the company carried out "micro-repairing tooth preparation", "digital occlusion force measurement", "full-scale digital planting" and other technologies, and published more than 20 professional articles. She has undertaken more than 10 projects of the National Natural Science Foundation and above.
Zhang Feng
Nanchang University Affiliated Stomatological Hospital, graduate student, graduated from Nanchang University School of Medicine in 2010. During the school, she has won scholarships and awards on campus. In 2012, she went to the South Nottingham College in the UK to attend the Summer School and obtained the certificate of completion. She is the co-patent holder of this series of work and the main experimental completion person.
